1 November 2011 Raman spectroscopic characterization and differentiation of seminal plasma
Author Affiliations +
J. of Biomedical Optics, 16(11), 110501 (2011). doi:10.1117/1.3650310
Abstract
Raman spectroscopy (RS) was applied for the analysis of seminal plasma in order to detect spectral parameters, which might be used for differentiating the normal and abnormal semen samples. Raman spectra of seminal plasma separated from normal and abnormal semen samples, showed a distinct difference in peak ratios between 1449 and 1418 cm−1 (P < 0.05). More efficient alternative method of using principal component analysis-linear discriminate analysis based on Raman spectroscopic data yielded a diagnostic sensitivity of 73% and specificity of 82%. The results suggest that RS combined with the multivariate analysis method has the potential for differentiating semen samples by examination of the corresponding seminal plasma.
Zufang Huang, Xiwen Chen, Yanping Chen, Shangyuan Feng, Rong Chen, Jinhua Chen, Min Dou, Haishan Zeng, "Raman spectroscopic characterization and differentiation of seminal plasma," Journal of Biomedical Optics 16(11), 110501 (1 November 2011). http://dx.doi.org/10.1117/1.3650310
Submission: Received ; Accepted
JOURNAL ARTICLE
4 PAGES


SHARE
KEYWORDS
Plasma

Raman spectroscopy

Statistical analysis

Remote sensing

Spectroscopy

Diagnostics

Solids

Back to Top