Retinal image restoration by means of blind deconvolution

Andres G. Marrugo; Maria S. Millan; Michal Sorel; Filip Sroubek

doi:10.1117/1.3652709

1 November 2011 Retinal image restoration by means of blind deconvolution

Andres G. Marrugo, Maria S. Millan, Michal Sorel, Filip Sroubek

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Journal of Biomedical Optics, Vol. 16, Issue 11, 116016 (November 2011). https://doi.org/10.1117/1.3652709

Abstract

Retinal imaging plays a key role in the diagnosis and management of ophthalmologic disorders, such as diabetic retinopathy, glaucoma, and age-related macular degeneration. Because of the acquisition process, retinal images often suffer from blurring and uneven illumination. This problem may seriously affect disease diagnosis and progression assessment. Here we present a method for color retinal image restoration by means of multichannel blind deconvolution. The method is applied to a pair of retinal images acquired within a lapse of time, ranging from several minutes to months. It consists of a series of preprocessing steps to adjust the images so they comply with the considered degradation model, followed by the estimation of the point-spread function and, ultimately, image deconvolution. The preprocessing is mainly composed of image registration, uneven illumination compensation, and segmentation of areas with structural changes. In addition, we have developed a procedure for the detection and visualization of structural changes. This enables the identification of subtle developments in the retina not caused by variation in illumination or blur. The method was tested on synthetic and real images. Encouraging experimental results show that the method is capable of significant restoration of degraded retinal images.

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Andres G. Marrugo, Maria S. Millan, Michal Sorel, and Filip Sroubek "Retinal image restoration by means of blind deconvolution," Journal of Biomedical Optics 16(11), 116016 (1 November 2011). https://doi.org/10.1117/1.3652709

Published: 1 November 2011

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