1 December 2011 Time-resolved imaging refractometry of microbicidal films using quantitative phase microscopy
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J. of Biomedical Optics, 16(12), 120510 (2011). doi:10.1117/1.3665439
Abstract
Quantitative phase microscopy is applied to image temporal changes in the refractive index (RI) distributions of solutions created by microbicidal films undergoing hydration. We present a novel method of using an engineered polydimethylsiloxane structure as a static phase reference to facilitate calibration of the absolute RI across the entire field. We present a study of dynamic structural changes in microbicidal films during hydration and subsequent dissolution. With assumptions about the smoothness of the phase changes induced by these films, we calculate absolute changes in the percentage of film in regions across the field of view.
Matthew T. Rinehart, Tyler K. Drake, Francisco E. Robles, Adam P. Wax, Lisa C. Rohan, David F. Katz, "Time-resolved imaging refractometry of microbicidal films using quantitative phase microscopy," Journal of Biomedical Optics 16(12), 120510 (1 December 2011). http://dx.doi.org/10.1117/1.3665439
Submission: Received ; Accepted
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KEYWORDS
Calibration

Microscopy

Water

Refractive index

Refractometry

Phase measurement

Interferometry

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