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1 April 2011 Endomicroscopy imaging of epithelial structures using tissue autofluorescence
Bevin Lin, Dennis L. Matthews, Stavros G. Demos, Shiro Urayama, Ramez M. G. Saroufeem
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Journal of Biomedical Optics, Vol. 16, Issue 4, 046014 (April 2011). https://doi.org/10.1117/1.3565216
Abstract
We explore autofluorescence endomicroscopy as a potential tool for real-time visualization of epithelial tissue microstructure and organization in a clinical setting. The design parameters are explored using two experimental systems-an Olympus Medical Systems Corp. stand-alone clinical prototype probe, and a custom built bench-top rigid fiber conduit prototype. Both systems entail ultraviolet excitation at 266 nm and/or 325 nm using compact laser sources. Preliminary results using ex vivo animal and human tissue specimens suggest that this technology can be translated toward in vivo application to address the need for real-time histology.
©(2011) Society of Photo-Optical Instrumentation Engineers (SPIE)
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Bevin Lin, Dennis L. Matthews, Stavros G. Demos, Shiro Urayama, and Ramez M. G. Saroufeem "Endomicroscopy imaging of epithelial structures using tissue autofluorescence," Journal of Biomedical Optics 16(4), 046014 (1 April 2011). https://doi.org/10.1117/1.3565216
Published: 1 April 2011
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Cited by 3 scholarly publications.
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KEYWORDS
Tissues
Atrial fibrillation
Imaging systems
Tissue optics
Endomicroscopy
Biopsy
Ultraviolet radiation
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