1 May 2011 Silver nanostructure sensing platform for maximum-contrast fluorescence cell imaging
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Abstract
We present herein a silver nanostructure-assisted sensing platform which consists of a combined structure of Ag nanowire (NW) and nanodot (ND) array. Highly enhanced fluorescence from fluorophore is attributed to a strongly coupled optical near-field interaction between proximately located Ag NW and NDs. We obtained enhanced fluorescence intensity with up to 140 folds, as contrasted from background intensity, reaching a theoretical maximum value. On the other hand, fluorescence lifetime was greatly reduced to 0.27 ns (from 2.17 ns for the same fluorophores without nanostructure). This novel platform can be a promising utility for optical imaging and labeling of biological systems with a great sensitivity.
© (2011) Society of Photo-Optical Instrumentation Engineers (SPIE)
Kyung-Min Lee, Kyung-Min Lee, Arup Neogi, Arup Neogi, Purnima B. Neogi, Purnima B. Neogi, Minjung Kim, Minjung Kim, Bongsoo Kim, Bongsoo Kim, Rafal Luchowski, Rafal Luchowski, Zygmunt K. Gryczynski, Zygmunt K. Gryczynski, Nils Calander, Nils Calander, Tae-Youl Choi, Tae-Youl Choi, } "Silver nanostructure sensing platform for maximum-contrast fluorescence cell imaging," Journal of Biomedical Optics 16(5), 056008 (1 May 2011). https://doi.org/10.1117/1.3579157 . Submission:
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