1 June 2011 Novel combined miniature optical coherence tomography ultrasound probe for in vivo intravascular imaging
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Abstract
We have developed a miniature integrated optical coherence tomography (OCT) ultrasound (US) probing system for intravascular imaging applications. In the OCT probe, the light coming out of a single mode fiber is focused by a gradient-index lens and then reflected by a right-angle prism from the side of the probe into the sample. It was combined with a 35 MHz PMN-PT side-viewing ultrasound transducer to obtain the ultrasound image as well. The OCT and ultrasound probes were integrated as a single probe to obtain OCT and ultrasound images simultaneously. The integrated probe has an outer diameter of 0.69 mm which, to our knowledge, is the smallest integrated OCT-US probe reported. Fast data acquisition and processing was implemented for real-time imaging. In vitro OCT and US images of human coronary artery with pathology, as well as in vivo images of normal rabbit abdominal aorta, were obtained using the integrated OCT-US probe to demonstrate its capability.
© (2011) Society of Photo-Optical Instrumentation Engineers (SPIE)
Jiechen Yin, Jiechen Yin, Jiawen Li, Jiawen Li, Zhongping Chen, Zhongping Chen, Xiang Li, Xiang Li, Kirk K. Shung, Kirk K. Shung, Qifa Zhou, Qifa Zhou, Joseph Jing, Joseph Jing, David Sho Mukai, David Sho Mukai, Sari B. Mahon, Sari B. Mahon, Matthew Brenner, Matthew Brenner, Ahmad Edris, Ahmad Edris, Ahmad Khiet C. Hoang, Ahmad Khiet C. Hoang, Jagat Narula, Jagat Narula, } "Novel combined miniature optical coherence tomography ultrasound probe for in vivo intravascular imaging," Journal of Biomedical Optics 16(6), 060505 (1 June 2011). https://doi.org/10.1117/1.3589097 . Submission:
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