Diagnosing dry eye with dynamic-area high-speed videokeratoscopy

David Alonso-Caneiro; Michael J. Collins; Jason Turuwhenua; D. Robert Iskander

doi:10.1117/1.3598837

1 July 2011 Diagnosing dry eye with dynamic-area high-speed videokeratoscopy

David Alonso-Caneiro, Michael J. Collins, Jason Turuwhenua, D. Robert Iskander

Author Affiliations +

Journal of Biomedical Optics, Vol. 16, Issue 7, 076012 (July 2011). https://doi.org/10.1117/1.3598837

Abstract

Dry eye syndrome is one of the most commonly reported eye health conditions. Dynamic-area high-speed videokeratoscopy (DA-HSV) represents a promising alternative to the most invasive clinical methods for the assessment of the tear film surface quality (TFSQ), particularly as Placido-disk videokeratoscopy is both relatively inexpensive and widely used for corneal topography assessment. Hence, improving this technique to diagnose dry eye is of clinical significance and the aim of this work. First, a novel ray-tracing model is proposed that simulates the formation of a Placido image. This model shows the relationship between tear film topography changes and the obtained Placido image and serves as a benchmark for the assessment of indicators of the ring's regularity. Further, a novel block-feature TFSQ indicator is proposed for detecting dry eye from a series of DA-HSV measurements. The results of the new indicator evaluated on data from a retrospective clinical study, which contains 22 normal and 12 dry eyes, have shown a substantial improvement of the proposed technique to discriminate dry eye from normal tear film subjects. The best discrimination was obtained under suppressed blinking conditions. In conclusion, this work highlights the potential of the DA-HSV as a clinical tool to diagnose dry eye syndrome.

©(2011) Society of Photo-Optical Instrumentation Engineers (SPIE)

Citation Download Citation

David Alonso-Caneiro, Michael J. Collins, Jason Turuwhenua, and D. Robert Iskander "Diagnosing dry eye with dynamic-area high-speed videokeratoscopy," Journal of Biomedical Optics 16(7), 076012 (1 July 2011). https://doi.org/10.1117/1.3598837

Published: 1 July 2011

ACCESS THE FULL ARTICLE

JOURNAL ARTICLE
9 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY