1 July 2011 Digital optical tomography system for dynamic breast imaging
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Abstract
Diffuse optical tomography has shown promising results as a tool for breast cancer screening and monitoring response to chemotherapy. Dynamic imaging of the transient response of the breast to an external stimulus, such as pressure or a respiratory maneuver, can provide additional information that can be used to detect tumors. We present a new digital continuous-wave optical tomography system designed to simultaneously image both breasts at fast frame rates and with a large number of sources and detectors. The system uses a master-slave digital signal processor-based detection architecture to achieve a dynamic range of 160 dB and a frame rate of 1.7 Hz with 32 sources, 64 detectors, and 4 wavelengths per breast. Included is a preliminary study of one healthy patient and two breast cancer patients showing the ability to identify an invasive carcinoma based on the hemodynamic response to a breath hold.
© (2011) Society of Photo-Optical Instrumentation Engineers (SPIE)
Molly L. Flexman, Molly L. Flexman, Michael A. Khalil, Michael A. Khalil, Hyun K. Kim, Hyun K. Kim, Christopher J. Fong, Christopher J. Fong, Andreas H. Hielscher, Andreas H. Hielscher, Rabah Al Abdi, Rabah Al Abdi, Randall L. Barbour, Randall L. Barbour, Elise Desperito, Elise Desperito, Dawn L. Hershman, Dawn L. Hershman, } "Digital optical tomography system for dynamic breast imaging," Journal of Biomedical Optics 16(7), 076014 (1 July 2011). https://doi.org/10.1117/1.3599955 . Submission:
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