1 July 2011 Studies on erythrocytes in malaria infected blood sample with Raman optical tweezers
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Abstract
Raman spectroscopy was performed on optically trapped red blood cells (RBCs) from blood samples of healthy volunteers (h-RBCs) and from patients suffering from P. vivax infection (m-RBCs). A significant fraction of m-RBCs produced Raman spectra with altered characteristics relative to h-RBCs. The observed spectral changes suggest a reduced oxygen-affinity or right shifting of the oxygen-dissociation curve for the intracellular hemoglobin in a significant fraction of m-RBCs with respect to its normal functional state.
© (2011) Society of Photo-Optical Instrumentation Engineers (SPIE)
Raktim Dasgupta, Ravi S. Verma, Sunita Ahlawat, Abha Uppal, Pradeep K. Gupta, "Studies on erythrocytes in malaria infected blood sample with Raman optical tweezers," Journal of Biomedical Optics 16(7), 077009 (1 July 2011). https://doi.org/10.1117/1.3600011 . Submission:
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