1 July 2011 Studies on erythrocytes in malaria infected blood sample with Raman optical tweezers
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Abstract
Raman spectroscopy was performed on optically trapped red blood cells (RBCs) from blood samples of healthy volunteers (h-RBCs) and from patients suffering from P. vivax infection (m-RBCs). A significant fraction of m-RBCs produced Raman spectra with altered characteristics relative to h-RBCs. The observed spectral changes suggest a reduced oxygen-affinity or right shifting of the oxygen-dissociation curve for the intracellular hemoglobin in a significant fraction of m-RBCs with respect to its normal functional state.
© (2011) Society of Photo-Optical Instrumentation Engineers (SPIE)
Raktim Dasgupta, Raktim Dasgupta, Ravi S. Verma, Ravi S. Verma, Sunita Ahlawat, Sunita Ahlawat, Abha Uppal, Abha Uppal, Pradeep K. Gupta, Pradeep K. Gupta, } "Studies on erythrocytes in malaria infected blood sample with Raman optical tweezers," Journal of Biomedical Optics 16(7), 077009 (1 July 2011). https://doi.org/10.1117/1.3600011 . Submission:
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