1 July 2011 Studies of inactivation of encephalomyocarditis virus, M13 bacteriophage, and Salmonella typhimurium by using a visible femtosecond laser: insight into the possible inactivation mechanisms
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Abstract
We report experimental results on the inactivation of encephalomyocarditis virus, M13 bacteriophage, and Salmonella typhimurium by a visible femtosecond laser. Our results suggest that inactivation of virus and bacterium by a visible femtosecond laser involves completely different mechanisms. Inactivation of viruses by a visible femtosecond laser involves the breaking of hydrogen/hydrophobic bonds or the separation of the weak protein links in the protein shell of a viral particle. In contrast, inactivation of bacteria is related to the damage of their DNAs due to irradiation of a visible femtosecond laser. Possible mechanisms for the inactivation of viruses and bacteria are discussed.
© (2011) Society of Photo-Optical Instrumentation Engineers (SPIE)
Kong-Thon Tsen, Stephanie Cope, Sara Vaiana, Shaw-Wei David Tsen, Qiang Fu, Stuart M. Lindsay, Zhe Li, Juliann G. Kiang, "Studies of inactivation of encephalomyocarditis virus, M13 bacteriophage, and Salmonella typhimurium by using a visible femtosecond laser: insight into the possible inactivation mechanisms," Journal of Biomedical Optics 16(7), 078003 (1 July 2011). https://doi.org/10.1117/1.3600771 . Submission:
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