8 November 2012 Study on application of optical clearing technique in skin diseases
Author Affiliations +
So far, the study of the optical clearing is almost always about healthy tissue. However, the ultimate goal is to detect diseases for clinical application. Optical clearing on diseased skins is explored. The effect is evaluated by applying a combined liquid paraffin and glycerol mixed solution on several kinds of diseased skins in vitro. Scanning experiments from optical coherence tomography show that it has different effects among fibroma, pigmented nevus, and seborrheic keratosis. Based on the results, we conclude that different skin diseases have different compositions and structures, and their optical parameters and biological characteristics should be different, which implies that the optical clearing technique may have selectivity and may not be suitable for all kinds of skin diseases.
© 2012 Society of Photo-Optical Instrumentation Engineers (SPIE)
Hao Shan, Hao Shan, Yanmei Liang, Yanmei Liang, Jingyi Wang, Jingyi Wang, Yan Li, Yan Li, } "Study on application of optical clearing technique in skin diseases," Journal of Biomedical Optics 17(11), 115003 (8 November 2012). https://doi.org/10.1117/1.JBO.17.11.115003 . Submission:

Back to Top