10 July 2012 Localized thermal mapping using coherent anti-Stokes Raman spectroscopy
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Abstract
Coherent anti-Stokes Raman scattering (CARS) spectroscopy is explored as a tool for obtaining micro-scale thermal measurements. A single femtosecond oscillator is used to pump a photonic crystal fiber to provide the broadband Stokes pulse. The CARS signals from the broad OH-stretching modes between 3000 and 3600 cm-1 are shown to correlate with temperature with an accuracy of ±1°C for water and ±1.5°C for phosphate-buffered saline. Local variation of temperature is mapped on a microscopic level, using black-dyed microspheres as thermal sources.
© 2012 Society of Photo-Optical Instrumentation Engineers (SPIE)
Hope T. Beier, Hope T. Beier, Benjamin A. Rockwell, Benjamin A. Rockwell, Gary D. Noojin, Gary D. Noojin, } "Localized thermal mapping using coherent anti-Stokes Raman spectroscopy," Journal of Biomedical Optics 17(8), 080501 (10 July 2012). https://doi.org/10.1117/1.JBO.17.8.080501 . Submission:
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