5 November 2013 Ultrasound-heated photoacoustic flowmetry
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Abstract
We report the development of photoacoustic flowmetry assisted by high-intensity focused ultrasound (HIFU). This novel method employs HIFU to generate a heating impulse in the flow medium, followed by photoacoustic monitoring of the thermal decay process. Photoacoustic flowmetry in a continuous medium remains a challenge in the optical diffusive regime. Here, both the HIFU heating and photoacoustic detection can focus at depths beyond the optical diffusion limit (∼1  mm in soft tissue). This method can be applied to a continuous medium, i.e., a medium without discrete scatterers or absorbers resolvable by photoacoustic imaging. Flow speeds up to 41  mm⋅s −1 have been experimentally measured in a blood phantom covered by 1.5-mm-thick tissue.
© 2013 Society of Photo-Optical Instrumentation Engineers (SPIE)
Lidai Wang, Lidai Wang, Junjie Yao, Junjie Yao, Konstantin I. Maslov, Konstantin I. Maslov, Wenxin Xing, Wenxin Xing, Lihong V. Wang, Lihong V. Wang, } "Ultrasound-heated photoacoustic flowmetry," Journal of Biomedical Optics 18(11), 117003 (5 November 2013). https://doi.org/10.1117/1.JBO.18.11.117003 . Submission:
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