12 February 2013 Color-matched and fluorescence-labeled esophagus phantom and its applications
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Abstract
We developed a stable, reproducible three-dimensional optical phantom for the evaluation of a wide-field endoscopic molecular imaging system. This phantom mimicked a human esophagus structure with flexibility to demonstrate body movements. At the same time, realistic visual appearance and diffuse spectral reflectance properties of the tissue were simulated by a color matching methodology. A photostable dye-in-polymer technology was applied to represent biomarker probed “hot-spot” locations. Furthermore, fluorescent target quantification of the phantom was demonstrated using a 1.2 mm ultrathin scanning fiber endoscope with concurrent fluorescence-reflectance imaging.
© 2013 Society of Photo-Optical Instrumentation Engineers (SPIE)
Chenying Yang, Vivian Hou, Leonard Y. Nelson, Eric J. Seibel, "Color-matched and fluorescence-labeled esophagus phantom and its applications," Journal of Biomedical Optics 18(2), 026020 (12 February 2013). https://doi.org/10.1117/1.JBO.18.2.026020 . Submission:
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