1 April 2013 Rapid quantification of pixel-wise fiber orientation data in micrographs
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Abstract
Defining fiber orientation at each pixel within a medical image has traditionally been computationally intensive and prone to systematic errors. A weighted orientation vector summation algorithm capable of detecting fiber orientation simultaneously at each pixel within an image is presented. As a result, pixel-specific fiber orientation information with 2 deg to 3 deg accuracy can be determined within seconds, enabling the practical use of pixel-wise orientation data for characterizing structural anisotropy. This analysis technique has applicability and potential diagnostic utility for a variety of modalities, including second harmonic generation, scanning electron microscopy and immunohistochemical imaging is demonstrated.
© 2013 Society of Photo-Optical Instrumentation Engineers (SPIE)
Kyle P. Quinn, Kyle P. Quinn, Irene Georgakoudi, Irene Georgakoudi, } "Rapid quantification of pixel-wise fiber orientation data in micrographs," Journal of Biomedical Optics 18(4), 046003 (1 April 2013). https://doi.org/10.1117/1.JBO.18.4.046003 . Submission:
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