5 March 2014 Compressed sensing based virtual-detector photoacoustic microscopy in vivo
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Abstract
Photoacoustic microscopy (PAM) is becoming a vital tool for various biomedical studies, including functional and molecular imaging of cancer. However, due to the use of a focused ultrasonic transducer for photoacoustic detection, the image quality of conventional PAM degrades rapidly away from the ultrasonic focal zone. To improve the image quality of PAM for out-of-focus regions, we have developed compressed sensing based virtual-detector photoacoustic microscopy (CS-PAM). Through phantom and in vivo experiments, it has been demonstrated that CS-PAM can effectively extend the depth of focus of PAM, and thus may greatly expand its potential biomedical applications.
© 2014 Society of Photo-Optical Instrumentation Engineers (SPIE)
Jing Meng, Chengbo Liu, Jiaxiang Zheng, Riqiang Lin, Liang Song, "Compressed sensing based virtual-detector photoacoustic microscopy in vivo," Journal of Biomedical Optics 19(3), 036003 (5 March 2014). https://doi.org/10.1117/1.JBO.19.3.036003 . Submission:
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