24 March 2014 In vivo detection of inhalation injury in large airway using three-dimensional long-range swept-source optical coherence tomography
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Abstract
We report on the feasibility of using long-range swept-source optical coherence tomography (OCT) to detect airway changes following smoke inhalation in a sheep model. The long-range OCT system (with axial imaging range of 25 mm) and probe are capable of rapidly obtaining a series of high-resolution full cross-sectional images and three-dimensional reconstructions covering 20-cm length of tracheal and bronchial airways with airway diameter up to 25 mm, regardless of the position of the probe within the airway lumen. Measurements of airway thickness were performed at baseline and postinjury to show mucosal thickness changes following smoke inhalation.
© 2014 Society of Photo-Optical Instrumentation Engineers (SPIE)
Lidek Chou, Lidek Chou, Andriy Batchinsky, Andriy Batchinsky, Slava Belenkiy, Slava Belenkiy, Joseph C. Jing, Joseph C. Jing, Tirunelvil Ramalingam, Tirunelvil Ramalingam, Matthew Brenner, Matthew Brenner, Zhongping Chen, Zhongping Chen, } "In vivo detection of inhalation injury in large airway using three-dimensional long-range swept-source optical coherence tomography," Journal of Biomedical Optics 19(3), 036018 (24 March 2014). https://doi.org/10.1117/1.JBO.19.3.036018 . Submission:
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