18 September 2014 Accommodation-induced variations in retinal thickness measured by spectral domain optical coherence tomography
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To research retinal stretching or distortion with accommodation, accommodation-induced changes in retinal thickness (RT) in the macular area were investigated in a population of young adults (n=23) by using a dual-channel spectral domain optical coherence tomography (SD-OCT) system manufactured in-house for this study. This dual-channel SD-OCT is capable of imaging the cornea and retina simultaneously with an imaging speed of 24 kHz A-line scan rate, which can provide the anatomical dimensions of the eye, including the RT and axial length. Thus, the modification of the RT with accommodation can be calculated. A significant decrease in the RT (13.50±1.25  μm) was observed during maximum accommodation. In the 4  mm×4  mm macular area centered at the fovea, we did not find a significant quadrant-dependent difference in retinal volume change, which indicates that neither retinal stretching nor distortion was quadrant-dependent during accommodation. We speculate that the changes in RT with maximum accommodation resulted from accommodation-induced ciliary muscle contractions.
© 2014 Society of Photo-Optical Instrumentation Engineers (SPIE)
Shanhui Fan, Yong Sun, Cuixia Dai, Haihua Zheng, Qiushi Ren, Shuliang Jiao, Chuanqing Zhou, "Accommodation-induced variations in retinal thickness measured by spectral domain optical coherence tomography," Journal of Biomedical Optics 19(9), 096012 (18 September 2014). https://doi.org/10.1117/1.JBO.19.9.096012

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