Fluorescence spectroscopy of dermal wounds in rats

Yuanlong Yang; Lee David Mitchell; Robert R. Alfano

doi:10.1117/12.259613

1 January 1997 Fluorescence spectroscopy of dermal wounds in rats

Yuanlong Yang, Lee David Mitchell, Robert R. Alfano

Author Affiliations +

Journal of Biomedical Optics, Vol. 2, Issue 1, (January 1997). https://doi.org/10.1117/12.259613

Abstract

Fluorescence spectra of dermal lesions on 48 rats were investigated using excitation wavelengths of 275, 300, and 340 nm. Emissions at 340 and 460 nm were measured in both the forequarter and hindquarter lesions as function of time after incision. Unlike the 460-nm emission, intensity at 340 nm increased with time and then saturated. Control studies on intact skin and lesions in dead rats failed to demonstrate any time-dependent changes at these wavelengths. It appears that the increase in the 340-nm intensity is due to changes in the tryptophan level, and may reflect accumulation of fibrinogen in the early wound healing process.

Citation Download Citation

Yuanlong Yang, Lee David Mitchell, and Robert R. Alfano "Fluorescence spectroscopy of dermal wounds in rats," Journal of Biomedical Optics 2(1), (1 January 1997). https://doi.org/10.1117/12.259613

Published: 1 January 1997

Access the abstract

JOURNAL ARTICLE
5 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY