29 July 2015 Spatiotemporal correlation of optical coherence tomography <italic<in-vivo</italic< images of rabbit airway for the diagnosis of edema
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J. of Biomedical Optics, 20(7), 076015 (2015). doi:10.1117/1.JBO.20.7.076015
Abstract
Detection of an early stage of subglottic edema is vital for airway management and prevention of stenosis, a life-threatening condition in critically ill neonates. As an observer for the task of diagnosing edema <italic<in vivo</italic<, we investigated spatiotemporal correlation (STC) of full-range optical coherence tomography (OCT) images acquired in the rabbit airway with experimentally simulated edema. Operating the STC observer on OCT images generates STC coefficients as test statistics for the statistical decision task. Resulting from this, the receiver operating characteristic (ROC) curves for the diagnosis of airway edema with full-range OCT <italic<in-vivo</italic< images were extracted and areas under ROC curves were calculated. These statistically quantified results demonstrated the potential clinical feasibility of the STC method as a means to identify early airway edema.
DongYel Kang, Alex Wang, Veronika Volgger, Zhongping Chen, Brian J. F. Wong, "Spatiotemporal correlation of optical coherence tomography <italic<in-vivo</italic< images of rabbit airway for the diagnosis of edema," Journal of Biomedical Optics 20(7), 076015 (29 July 2015). http://dx.doi.org/10.1117/1.JBO.20.7.076015
Submission: Received ; Accepted
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KEYWORDS
Optical coherence tomography

In vivo imaging

Tissues

Image segmentation

Binary data

Speckle

Imaging systems

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