20 January 2015 Image overlay solution based on threshold detection for a compact near infrared fluorescence goggle system
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Abstract
Near infrared (NIR) fluorescence imaging has shown great potential for various clinical procedures, including intraoperative image guidance. However, existing NIR fluorescence imaging systems either have a large footprint or are handheld, which limits their usage in intraoperative applications. We present a compact NIR fluorescence imaging system (NFIS) with an image overlay solution based on threshold detection, which can be easily integrated with a goggle display system for intraoperative guidance. The proposed NFIS achieves compactness, light weight, hands-free operation, high-precision superimposition, and a real-time frame rate. In addition, the miniature and ultra-lightweight light-emitting diode tracking pod is easy to incorporate with NIR fluorescence imaging. Based on experimental evaluation, the proposed NFIS solution has a lower detection limit of 25 nM of indocyanine green at 27 fps and realizes a highly precise image overlay of NIR and visible images of mice
© 2015 Society of Photo-Optical Instrumentation Engineers (SPIE)
Shengkui Gao, Suman B. Mondal, Nan Zhu, RongGuang Liang, Samuel Achilefu, Viktor Gruev, "Image overlay solution based on threshold detection for a compact near infrared fluorescence goggle system," Journal of Biomedical Optics 20(1), 016018 (20 January 2015). https://doi.org/10.1117/1.JBO.20.1.016018 . Submission:
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