8 May 2015 Laser beam coupling into nerve fiber myelin allows one to assess its structural membrane properties
Author Affiliations +
Abstract
We show that myelin, the insulation wrap of nerve fibers, can couple laser light, thus behaving as a single-cell optical device. The effect was employed to map distinct myelin regions based on the coupling efficiency. Raman spectra acquisition allowed us to simultaneously understand the underlying microscopic differences in the membrane lipid ordering degree. The described method potentially provides new capabilities in myelin-associated disease studies and can be used as a handy tool for myelin structure investigation in combination with other methods.
© 2015 Society of Photo-Optical Instrumentation Engineers (SPIE)
Nikolay P. Kutuzov, Alexey R. Brazhe, Vladimir L. Lyaskovskiy, Georgy Maksimov, "Laser beam coupling into nerve fiber myelin allows one to assess its structural membrane properties," Journal of Biomedical Optics 20(5), 050501 (8 May 2015). https://doi.org/10.1117/1.JBO.20.5.050501 . Submission:
JOURNAL ARTICLE
3 PAGES


SHARE
RELATED CONTENT

Fiber optical beam shaping using polymeric structures
Proceedings of SPIE (June 02 2014)
Raman technology for future planetary missions
Proceedings of SPIE (November 21 2017)
Nonlinear operation of fiber distributed-feedback lasers
Proceedings of SPIE (August 01 1991)
Cladded optical fiber laser made from a axis Nd MgO...
Proceedings of SPIE (September 20 1999)
Reliability of high-power multi-mode pump modules
Proceedings of SPIE (October 08 2004)

Back to Top