8 May 2015 Laser beam coupling into nerve fiber myelin allows one to assess its structural membrane properties
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Abstract
We show that myelin, the insulation wrap of nerve fibers, can couple laser light, thus behaving as a single-cell optical device. The effect was employed to map distinct myelin regions based on the coupling efficiency. Raman spectra acquisition allowed us to simultaneously understand the underlying microscopic differences in the membrane lipid ordering degree. The described method potentially provides new capabilities in myelin-associated disease studies and can be used as a handy tool for myelin structure investigation in combination with other methods.
© 2015 Society of Photo-Optical Instrumentation Engineers (SPIE)
Nikolay P. Kutuzov, Nikolay P. Kutuzov, Alexey R. Brazhe, Alexey R. Brazhe, Vladimir L. Lyaskovskiy, Vladimir L. Lyaskovskiy, Georgy Maksimov, Georgy Maksimov, } "Laser beam coupling into nerve fiber myelin allows one to assess its structural membrane properties," Journal of Biomedical Optics 20(5), 050501 (8 May 2015). https://doi.org/10.1117/1.JBO.20.5.050501 . Submission:
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