18 May 2015 Optimal flushing agents for integrated optical and acoustic imaging systems
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An increasing number of integrated optical and acoustic intravascular imaging systems have been developed and hold great promise for accurately diagnosing vulnerable plaques and guiding atherosclerosis treatment. However, in any intravascular environment, the vascular lumen is filled with blood, a high-scattering source for optical and high-frequency ultrasound signals. Blood must be flushed away to provide clearer images. To our knowledge, no research has been performed to find the ideal flushing agent for combined optical and acoustic imaging techniques. We selected three solutions as potential flushing agents for their image-enhancing effects: mannitol, dextran, and iohexol. Testing of these flushing agents was performed in a closed-loop circulation model and
© 2015 Society of Photo-Optical Instrumentation Engineers (SPIE)
Jiawen Li, Hataka Minami, Earl Steward, Teng Ma, Dilbahar Mohar, Claire Robertson, Kirk Shung, Qifa Zhou, Pranav Patel, Zhongping Chen, "Optimal flushing agents for integrated optical and acoustic imaging systems," Journal of Biomedical Optics 20(5), 056005 (18 May 2015). https://doi.org/10.1117/1.JBO.20.5.056005 . Submission:

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