22 May 2015 Optical coherence tomography system requirements for clinical diagnostic middle ear imaging
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Abstract
Noninvasive middle ear imaging using optical coherence tomography (OCT) presents some unique challenges for real-time, clinical use in humans. We present results from a two-dimensional/three-dimensional OCT system built to assess the imaging requirements of clinical middle ear imaging, and the technical challenges associated with them. These include the need to work at a low numerical aperture, the deleterious effects of transtympanic imaging on image quality at the ossicles, sensitivity requirements for clinical fidelity of images at real-time rates, and the high dynamic-range requirements of the ear. We validated the system by imaging cadaveric specimens with simulated disorders to show the clinical applicability of the images. We also provide additional insight into the likely role of OCT in clinical otology.
© 2015 Society of Photo-Optical Instrumentation Engineers (SPIE)
Dan MacDougall, Dan MacDougall, James Rainsbury, James Rainsbury, Jeremy A. Brown, Jeremy A. Brown, Manohar Bance, Manohar Bance, Robert Adamson, Robert Adamson, } "Optical coherence tomography system requirements for clinical diagnostic middle ear imaging," Journal of Biomedical Optics 20(5), 056008 (22 May 2015). https://doi.org/10.1117/1.JBO.20.5.056008 . Submission:
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