13 July 2015 In vivo microvascular network imaging of the human retina combined with an automatic three-dimensional segmentation method
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Abstract
Microvascular network of the retina plays an important role in diagnosis and monitoring of various retinal diseases. We propose a three-dimensional (3-D) segmentation method with intensity-based Doppler variance (IBDV) based on swept-source optical coherence tomography. The automatic 3-D segmentation method is used to obtain seven surfaces of intraretinal layers. The microvascular network of the retina, which is acquired by the IBDV method, can be divided into six layers. The microvascular network of the six individual layers is visualized, and the morphology and contrast images can be improved by using the segmentation method. This method has potential for earlier diagnosis and precise monitoring in retinal vascular diseases.
© 2015 Society of Photo-Optical Instrumentation Engineers (SPIE)
Shenghai Huang, Zhonglie Piao, Jiang Zhu, Fan Lu, Zhongping Chen, "In vivo microvascular network imaging of the human retina combined with an automatic three-dimensional segmentation method," Journal of Biomedical Optics 20(7), 076003 (13 July 2015). https://doi.org/10.1117/1.JBO.20.7.076003 . Submission:
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