Lensless two-photon imaging through a multicore fiber with coherence-gated digital phase conjugation

Donald B. Conkey; Nicolino Stasio; Edgar E. Morales-Delgado; Marilisa Romito; Christophe Moser; Demetri Psaltis

doi:10.1117/1.JBO.21.4.045002

18 April 2016 Lensless two-photon imaging through a multicore fiber with coherence-gated digital phase conjugation

Donald B. Conkey, Nicolino Stasio, Edgar E. Morales-Delgado, Marilisa Romito, Christophe Moser, Demetri Psaltis

Author Affiliations +

Journal of Biomedical Optics, Vol. 21, Issue 4, 045002 (April 2016). https://doi.org/10.1117/1.JBO.21.4.045002

Abstract

We performed near-diffraction limited two-photon fluorescence (TPF) imaging through a lensless, multicore-fiber (MCF) endoscope utilizing digital phase conjugation. The phase conjugation technique is compatible with commercially available MCFs with high core density. We demonstrate focusing of ultrashort pulses through an MCF and show that the method allows for resolution that is not limited by the MCF core spacing. We constructed TPF images of fluorescent beads and cells by digital scanning of the phase-conjugated focus on the target object and collection of the emitted fluorescence through the MCF.

CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

Citation Download Citation

Donald B. Conkey, Nicolino Stasio, Edgar E. Morales-Delgado, Marilisa Romito, Christophe Moser, and Demetri Psaltis "Lensless two-photon imaging through a multicore fiber with coherence-gated digital phase conjugation," Journal of Biomedical Optics 21(4), 045002 (18 April 2016). https://doi.org/10.1117/1.JBO.21.4.045002

Published: 18 April 2016

ACCESS THE FULL ARTICLE

JOURNAL ARTICLE
9 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

CITATIONS

Cited by 30 scholarly publications and 3 patents.

Explore citations on Lens.org

KEYWORDS

Phase conjugation

Holograms

Two photon imaging

Calibration

Endoscopes

Diffraction

Spatial light modulators

Show All Keywords

RELATED CONTENT

Limited-angle holographic tomography with optically controlled projection generation
Proceedings of SPIE (March 09 2015)

Microscopy with multimode fibers
Proceedings of SPIE (May 23 2013)

Fluorescence and optical-resolution photoacoustic imaging through capillary waveguides
Proceedings of SPIE (March 15 2016)

Holographic endoscope based on coherent fiber bundles and adaptive optics...
Proceedings of SPIE (January 01 1900)

Ultrathin endoscopes nonlinear lensless imaging at the tip of...
Proceedings of SPIE (January 01 1900)

Two photon fluorescence imaging through multicore fiber with digital phase...
Proceedings of SPIE (March 15 2016)

Imaging and pattern projection through multicore fibers using the memory...
Proceedings of SPIE (June 26 2017)

Subscribe to Digital Library

Receive Erratum Email Alert

Show All Keywords

Keywords/Phrases

Search In:

Publication Years