12 July 2016 Continuous-terahertz-wave molecular imaging system for biomedical applications
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Abstract
Molecular imaging techniques are becoming increasingly important in biomedical research and potentially in clinical practice. We present a continuous-terahertz (THz)-wave molecular imaging system for biomedical applications, in which an infrared (IR) laser is integrated into a 0.2-THz reflection-mode continuous-THz-wave imaging system to induce surface plasmon polaritons on the nanoparticles and further improve the intensity of the reflected signal from the water around the nanoparticles. A strong and rapid increment of the reflected THz signal in the nanoparticle solution upon the IR laser irradiation is demonstrated, using either gold or silver nanoparticles. This low-cost, simple, and stable continuous-THz-wave molecular imaging system is suitable for miniaturization and practical imaging applications; in particular, it shows great promise for cancer diagnosis and nanoparticle drug-delivery monitoring.
© 2016 Society of Photo-Optical Instrumentation Engineers (SPIE)
Rui Zhang, Rui Zhang, Liangliang Zhang, Liangliang Zhang, Tong Wu, Tong Wu, Ruixue Wang, Ruixue Wang, Shasha Zuo, Shasha Zuo, Dong Wu, Dong Wu, Cunlin Zhang, Cunlin Zhang, Jue Zhang, Jue Zhang, Jing Fang, Jing Fang, } "Continuous-terahertz-wave molecular imaging system for biomedical applications," Journal of Biomedical Optics 21(7), 076006 (12 July 2016). https://doi.org/10.1117/1.JBO.21.7.076006 . Submission:
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