12 September 2016 Lorentz force optical coherence elastography
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Abstract
Quantifying tissue biomechanical properties can assist in detection of abnormalities and monitoring disease progression and/or response to a therapy. Optical coherence elastography (OCE) has emerged as a promising technique for noninvasively characterizing tissue biomechanical properties. Several mechanical loading techniques have been proposed to induce static or transient deformations in tissues, but each has its own areas of applications and limitations. This study demonstrates the combination of Lorentz force excitation and phase-sensitive OCE at ∼1.5  million A-lines per second to quantify the elasticity of tissue by directly imaging Lorentz force-induced elastic waves. This method of tissue excitation opens the possibility of a wide range of investigations using tissue biocurrents and conductivity for biomechanical analysis.
© 2016 Society of Photo-Optical Instrumentation Engineers (SPIE)
Chen Wu, Manmohan Singh, Zhaolong Han, Raksha Raghunathan, Chih-Hao Liu, Jiasong Li, Alexander Schill, Kirill V. Larin, "Lorentz force optical coherence elastography," Journal of Biomedical Optics 21(9), 090502 (12 September 2016). https://doi.org/10.1117/1.JBO.21.9.090502 . Submission:
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