9 September 2016 Investigation of alterations in multifractality in optical coherence tomographic images of in vivo human retina
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Abstract
Optical coherence tomography (OCT) enables us to monitor alterations in the thickness of the retinal layer as disease progresses in the human retina. However, subtle morphological changes in the retinal layers due to early disease progression often may not lead to detectable alterations in the thickness. OCT images encode depth-dependent backscattered intensity distribution arising due to the depth distributions of the refractive index from tissue microstructures. Here, such depth-resolved refractive index variations of different retinal layers were analyzed using multifractal detrended fluctuation analysis, a special class of multiresolution analysis tools. The analysis extracted and quantified microstructural multifractal information encoded in normal as well as diseased human retinal OCT images acquired
© 2016 Society of Photo-Optical Instrumentation Engineers (SPIE)
Nandan Kumar Das, Nandan Kumar Das, Sabyasachi Mukhopadhyay, Sabyasachi Mukhopadhyay, Nirmalya Ghosh, Nirmalya Ghosh, Jay Chhablani, Jay Chhablani, Ashutosh Richhariya, Ashutosh Richhariya, Kompalli Divakar Rao, Kompalli Divakar Rao, Naba Kishore Sahoo, Naba Kishore Sahoo, } "Investigation of alterations in multifractality in optical coherence tomographic images of in vivo human retina," Journal of Biomedical Optics 21(9), 096004 (9 September 2016). https://doi.org/10.1117/1.JBO.21.9.096004 . Submission:
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