16 September 2016 Reproducibility, interchangeability of measures, time to measure stabilization, and reference values of two tissue oximeters in healthy volunteers
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Abstract
This study aimed to compare two tissue oximeters, the INVOS 5100c and the Equanox 7600, in terms of their reproducibility and the interchangeability of their measures. In a randomized order, three measurements were taken at six different sites on both sides of the body in 53 healthy volunteers. Intraclass correlation coefficients (ICC) and within-subject standard deviation (Sw) were calculated for each device. The ICCs were compared using Fisher r-to-z transformation and the Sw were compared using paired-sample t-tests. We found no difference between the reproducibility of the INVOS {ICC=0.92 [95% confidence interval (CI) 0.90 to 0.93]} and Equanox [ICC=0.90 (95% CI 0.88 to 0.93)] in terms of ICCs (p=0.06). However, the Equanox [Sw=1.96 (95% CI 1.91 to 2.02)] showed a better Sw than the INVOS [Sw=2.11 (95% CI 2.05 to 2.17)] (p=0.019). Also, when compared directly to stable condition, the readings produced by the two oximeters varied considerably [ICC 0.43 (95% CI 0.36 to 0.49)]. When taken individually, both tissue oximeters displayed good reproducibility, the Equanox being slightly better than the INVOS in terms of absolute reproducibility. However, when compared, the oximeters showed poor interdevices agreement. Reference values were also described.
© 2016 Society of Photo-Optical Instrumentation Engineers (SPIE)
Alexis Cournoyer, Alexis Cournoyer, André Denault, André Denault, Sylvie Cossette, Sylvie Cossette, Annik Fortier, Annik Fortier, Raoul Daoust, Raoul Daoust, Massimiliano Iseppon, Massimiliano Iseppon, Jean-Marc Chauny, Jean-Marc Chauny, Eric Notebaert, Eric Notebaert, } "Reproducibility, interchangeability of measures, time to measure stabilization, and reference values of two tissue oximeters in healthy volunteers," Journal of Biomedical Optics 21(9), 097003 (16 September 2016). https://doi.org/10.1117/1.JBO.21.9.097003 . Submission:
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