1 November 2017 Multiscale sensorless adaptive optics OCT angiography system for in vivo human retinal imaging
Author Affiliations +
J. of Biomedical Optics, 22(12), 121703 (2017). doi:10.1117/1.JBO.22.12.121703
Abstract
We present a multiscale sensorless adaptive optics (SAO) OCT system capable of imaging retinal structure and vasculature with various fields-of-view (FOV) and resolutions. Using a single deformable mirror and exploiting the polarization properties of light, the SAO-OCT-A was implemented in a compact and easy to operate system. With the ability to adjust the beam diameter at the pupil, retinal imaging was demonstrated at two different numerical apertures with the same system. The general morphological structure and retinal vasculature could be observed with a few tens of micrometer-scale lateral resolution with conventional OCT and OCT-A scanning protocols with a 1.7-mm-diameter beam incident at the pupil and a large FOV ( 15 deg × 15 deg ). Changing the system to a higher numerical aperture with a 5.0-mm-diameter beam incident at the pupil and the SAO aberration correction, the FOV was reduced to 3 deg × 3 deg for fine detailed imaging of morphological structure and microvasculature such as the photoreceptor mosaic and capillaries. Multiscale functional SAO-OCT imaging was performed on four healthy subjects, demonstrating its functionality and potential for clinical utility.
© 2017 Society of Photo-Optical Instrumentation Engineers (SPIE)
Myeong Jin Ju, Morgan Heisler, Daniel Wahl, Yifan Jian, Marinko V. Sarunic, "Multiscale sensorless adaptive optics OCT angiography system for in vivo human retinal imaging," Journal of Biomedical Optics 22(12), 121703 (1 November 2017). https://doi.org/10.1117/1.JBO.22.12.121703 Submission: Received 2 August 2017; Accepted 5 October 2017
Submission: Received 2 August 2017; Accepted 5 October 2017
JOURNAL ARTICLE
10 PAGES


SHARE
Back to Top