23 January 2017 Taking advantage of acoustic inhomogeneities in photoacoustic measurements
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This paper proposes a method for improving the localization and the quantification of the optical parameters in photoacoustic (PA) tomography of biological tissues that are intrinsically heterogeneous in both optical and acoustic properties. It is based on the exploitation of both the PA signal, generated by the heterogeneous optical structures, and the secondary acoustic echoes due to the interaction between a primary PA wave generated near the tissue surface and the heterogeneous acoustic structures. These secondary echoes can also be collected through proper measurements of the PA signals. The experimental procedure is presented along with the method to filter the signal and the reconstruction algorithm that includes the account of the acoustic information.
© 2017 Society of Photo-Optical Instrumentation Engineers (SPIE)
Anabela Da Silva, Anabela Da Silva, Charles Handschin, Charles Handschin, Khaled Metwally, Khaled Metwally, Houssem Garci, Houssem Garci, Christophe Riedinger, Christophe Riedinger, Serge Mensah, Serge Mensah, Hassan Akhouayri, Hassan Akhouayri, } "Taking advantage of acoustic inhomogeneities in photoacoustic measurements," Journal of Biomedical Optics 22(4), 041012 (23 January 2017). https://doi.org/10.1117/1.JBO.22.4.041012 . Submission: Received: 1 September 2016; Accepted: 27 December 2016
Received: 1 September 2016; Accepted: 27 December 2016; Published: 23 January 2017

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