8 May 2017 Colposcopic imaging using visible-light optical coherence tomography
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Abstract
High-resolution colposcopic optical coherence tomography (OCT) provides key anatomical measures, such as thickness and minor traumatic injury of vaginal epithelium, of the female reproductive tract noninvasively. This information can be helpful in both fundamental investigations in animal models and disease screenings in humans. We present a fiber-based visible-light OCT and two probe designs for colposcopic application. One probe conducts circular scanning using a DC motor, and the other probe is capable of three-dimensional imaging over a 4.6 × 4.6 - mm 2 area using a pair of galvo scanners. Using this colposcopic vis-OCT with both probes, we acquired high-resolution images from whole isolated macaque vaginal samples and identified biopsy lesions.
© 2017 Society of Photo-Optical Instrumentation Engineers (SPIE)
Lian Duan, Lian Duan, Michael D. McRaven, Michael D. McRaven, Wenzhong Liu, Wenzhong Liu, Xiao Shu, Xiao Shu, Jianmin Hu, Jianmin Hu, Cheng Sun, Cheng Sun, Ronald S. Veazey, Ronald S. Veazey, Thomas J. Hope, Thomas J. Hope, Hao F. Zhang, Hao F. Zhang, } "Colposcopic imaging using visible-light optical coherence tomography," Journal of Biomedical Optics 22(5), 056003 (8 May 2017). https://doi.org/10.1117/1.JBO.22.5.056003 . Submission: Received: 11 January 2017; Accepted: 17 April 2017
Received: 11 January 2017; Accepted: 17 April 2017; Published: 8 May 2017
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