29 August 2017 Use of Mueller matrix polarimetry and optical coherence tomography in the characterization of cervical collagen anisotropy
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Abstract
Preterm birth (PTB) presents a serious medical health concern throughout the world. There is a high incidence of PTB in both developed and developing countries ranging from 11% to 15%, respectively. Recent research has shown that cervical collagen orientation and distribution changes during pregnancy may be useful in predicting PTB. Polarization imaging is an effective means to measure optical anisotropy in birefringent materials, such as the cervix’s extracellular matrix. Noninvasive, full-field Mueller matrix polarimetry (MMP) imaging methodologies, and optical coherence tomography (OCT) imaging were used to assess cervical collagen content and structure in nonpregnant porcine cervices. We demonstrate that the highly ordered structure of the nonpregnant porcine cervix can be observed with MMP. Furthermore, when utilized
© 2017 Society of Photo-Optical Instrumentation Engineers (SPIE)
Joseph Chue-Sang, Joseph Chue-Sang, Yuqiang Bai, Yuqiang Bai, Susan Stoff, Susan Stoff, Mariacarla Gonzalez, Mariacarla Gonzalez, Nola A. Holness, Nola A. Holness, Jefferson Gomes, Jefferson Gomes, Ranu Jung, Ranu Jung, Amir H. Gandjbakhche, Amir H. Gandjbakhche, Viktor V. Chernomordik, Viktor V. Chernomordik, Jessica C. Ramella-Roman, Jessica C. Ramella-Roman, } "Use of Mueller matrix polarimetry and optical coherence tomography in the characterization of cervical collagen anisotropy," Journal of Biomedical Optics 22(8), 086010 (29 August 2017). https://doi.org/10.1117/1.JBO.22.8.086010 . Submission: Received: 10 April 2017; Accepted: 24 July 2017
Received: 10 April 2017; Accepted: 24 July 2017; Published: 29 August 2017
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