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18 September 2017 Development of a reliable and reproducible phantom manufacturing method using silica microspheres in silicone
Charlotte J. Maughan Jones, Peter R. T. Munro
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Journal of Biomedical Optics, Vol. 22, Issue 9, 095004 (September 2017). https://doi.org/10.1117/1.JBO.22.9.095004
Abstract
Optically scattering phantoms composed of silica microspheres embedded in an optically clear silicone matrix were manufactured using a previously developed method. Multiple problems, such as sphere aggregation, adsorption to the cast, and silicone shrinkage, were, however, frequently encountered. Solutions to these problems were developed and an improved method, incorporating these solutions, is presented. The improved method offers excellent reliability and reproducibility for creating phantoms with uniform scattering coefficient. We also present evidence of decreased sphere aggregation.
CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
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Charlotte J. Maughan Jones and Peter R. T. Munro "Development of a reliable and reproducible phantom manufacturing method using silica microspheres in silicone," Journal of Biomedical Optics 22(9), 095004 (18 September 2017). https://doi.org/10.1117/1.JBO.22.9.095004
Received: 7 June 2017; Accepted: 28 August 2017; Published: 18 September 2017
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Cited by 6 scholarly publications and 1 patent.
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KEYWORDS
Silicon
Optical spheres
Scattering
Manufacturing
Silica
Optics manufacturing
Glasses
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