12 April 2018 Weak light emission of soft tissues induced by heating
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The main goal of this work is to show that soft tissue interaction with high-intensity focused ultrasound (HIFU) or direct heating leads to a weak light emission detectable using a small animal optical imaging system. Our results show that the luminescence signal is detectable after 30 min of heating, resembling the time scale of delayed luminescence. The imaging of a soft tissue after heating it using an HIFU field shows that the luminescence pattern closely matches the shape of the cone typical of the HIFU beam. We conclude that heating a soft tissue using two different sources leads to the emission of a weak luminescence signal from the heated region with a decay half-life of a few minutes (4 to 6 min). The origin of such light emission needs to be further investigated.
© 2018 Society of Photo-Optical Instrumentation Engineers (SPIE)
Antonello E. Spinelli, Antonello E. Spinelli, Giovanni Durando, Giovanni Durando, Federico Boschi, Federico Boschi, } "Weak light emission of soft tissues induced by heating," Journal of Biomedical Optics 23(4), 046003 (12 April 2018). https://doi.org/10.1117/1.JBO.23.4.046003 . Submission: Received: 4 January 2018; Accepted: 19 March 2018
Received: 4 January 2018; Accepted: 19 March 2018; Published: 12 April 2018

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