Advance in our knowledge of the molecular organization of living material rests on two kinds of technological development: (1) microscope instrumentation and (2) specimen preparation. This includes new techniques appropriate for a specific mode of microscopy, and information on any structural alterations produced during such specimen preparation.
Hans Ris, Hans Ris,
"Book Review, The Science of Biological Specimen Preparation for Microscopy by M. Malecki and G. M. Roomans," Journal of Biomedical Optics 4(1), (1 January 1999). https://doi.org/10.1117/1.429947