1 July 2000 Changes in cerebral hemoglobin concentration and oxygen saturation immediately after birth in the human neonate using full-spectrum near infrared spectroscopy
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J. of Biomedical Optics, 5(3), (2000). doi:10.1117/1.429997
Abstract
Using full-spectrum near infrared spectroscopy (fsNIRS), we measured changes in oxy- and deoxyhemoglobin (HbO2 and Hb), total hemoglobin (T-Hb) concentration, and hemoglobin oxygen saturation (SbO2) in the brain tissue of seven neonates immediately following birth. It was found that HbO2 rose rapidly within 2–3 min after birth. During the same time, there was a transient increase in T-Hb concentration, after which it decreased together with Hb. SbO2 increased rapidly after birth, from 18% at 1.5 min to about 55% at 5–6 min, followed by a gradual increase of about 10%. Oxygenation in the brain occurred much sooner in three subjects given oxygen for a short time immediately after birth than in those who did not receive oxygen. This preliminary study indicated that dynamic changes occur in cerebral circulation and oxygenation as part of the physiological changes taking place soon after birth.
Kenichi Isobe, Takashi Kusaka, Yuka Fujikawa, Masatoshi Kondo, Kou Kawada, Saneyuki Yasuda, Susumu Itoh, Konumu Hirao, Shoju Onishi, "Changes in cerebral hemoglobin concentration and oxygen saturation immediately after birth in the human neonate using full-spectrum near infrared spectroscopy," Journal of Biomedical Optics 5(3), (1 July 2000). http://dx.doi.org/10.1117/1.429997
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KEYWORDS
Oxygen

Brain

Near infrared spectroscopy

Tissues

Optical fibers

Tissue optics

Diffusion

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