1 July 2000 Comparison of macular versus paramacular retinal sensitivity to femtosecond laser pulses
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Single 130 fs laser pulses in the near-IR (800 nm) were used to create ophthalmoscopically viewed minimum visible lesions (MVLs) within the macular and paramacular regions in rhesus monkey eyes. MVL thresholds at 1 and 24 h are reported as the 50% probability for damage (ED50) together with their fiducial limits at the 95% confidence level. These measured thresholds are compared with previously reported thresholds for near-IR and visible wavelengths for both macular and paramacular areas. Threshold doses were lower at the 24 h reading than at the 1 h reading for both retinal regions and the ED50s for the macula were slightly lower than for the paramacula. We measured the 24 h MVL ED50 thresholds to be 0.35 and 0.55 µJ for the macular and paramacular areas, respectively. The combined data for both areas yielded a threshold of 0.45 µJ.
Clarence P. Cain, Clarence P. Cain, Cynthia A. Toth, Cynthia A. Toth, Robert J. Thomas, Robert J. Thomas, Gary D. Noojin, Gary D. Noojin, Val Carothers, Val Carothers, David J. Stolarski, David J. Stolarski, Benjamin A. Rockwell, Benjamin A. Rockwell, } "Comparison of macular versus paramacular retinal sensitivity to femtosecond laser pulses," Journal of Biomedical Optics 5(3), (1 July 2000). https://doi.org/10.1117/1.430002 . Submission:

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