1 July 2003 Metal-enhanced emission from indocyanine green: a new approach to in vivo imaging
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Abstract
Indocyanine green (ICG) is widely used in medical imaging and testing. Its complex spectral behavior and low quantum yield limits some applications. We show that proximity of ICG to a metallic silver particle increases its intensity approximately 20-fold and decreases the decay time. Since the rate of photobleaching is not increased, our results suggest that ICG-silver particle complexes can yield at least 20-fold more photons per ICG molecule for improved medical imaging.
© (2003) Society of Photo-Optical Instrumentation Engineers (SPIE)
Joanna B. Malicka, Joanna B. Malicka, Ignacy Gryczynski, Ignacy Gryczynski, Chris D. Geddes, Chris D. Geddes, Joseph R. Lakowicz, Joseph R. Lakowicz, } "Metal-enhanced emission from indocyanine green: a new approach to in vivo imaging," Journal of Biomedical Optics 8(3), (1 July 2003). https://doi.org/10.1117/1.1578643 . Submission:
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