1 July 2003 Subsurface skin renewal by treatment with a 1450-nm laser in combination with dynamic cooling
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Abstract
A new nonablative laser device, Smoothbeam, has been under evaluation for nonablative wrinkle reduction in skin with minimal side effects. This device incorporates a laser at 1450-nm wavelength to heat the dermis and cryogen spray cooling to prevent epidermal damage. The thermal injury created is internal and imperceptible. The wound-healing response to this internal injury causes improvement in the appearance of skin wrinkles. Biopsies taken immediately after treatment showed mild residual thermal damage (RTD) at a depth range of 150 to 400 μm, which is the dermal zone where most solar elastosis resides. Biopsies from two months after treatment showed fibroplasia extending over a range of depths similar to the acute RTD zones. An improvement in wrinkle severity was noted on the treated side compared with the control side.
Dilip Y. Paithankar, Joan M. Clifford, Bilal A. Saleh, E. Victor Ross, Christina A. Hardaway, David Barnette, "Subsurface skin renewal by treatment with a 1450-nm laser in combination with dynamic cooling," Journal of Biomedical Optics 8(3), (1 July 2003). https://doi.org/10.1117/1.1586703
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