1 January 2004 Combined multiplanar optical coherence tomography and confocal scanning ophthalmoscopy
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J. of Biomedical Optics, 9(1), (2004). doi:10.1117/1.1627778
Abstract
We demonstrate the clinical application of a multiplanar imaging system that simultaneously acquires en face (C-scan) optical coherence tomography (OCT) and the corresponding confocal ophthalmoscopic images, along with cross-sectional (B-scan) OCT at specifiable locations on the confocal image. The advantages of the simultaneous OCT and confocal acquisition as well as the challenges of interpreting the C-scan OCT images are discussed. Variations in tissue inclination with respect to the coherence wave surface alter the sampling of structures within the depth of the retina, producing novel slice orientations that are often challenging to interpret. We have evaluated for the first time the utility of C-scan OCT for a variety of pathologies, including melanocytoma, diabetic retinopathy, choroidal neovascular membrane, and macular pucker. Several remarkable new aspects of clinical anatomy were revealed using this new technique. The versatility of selective capture of C-scan OCT images and B-scan OCT images at precise points on the confocal image affords the clinician a more complete and interactive tool for 3-D imaging of retinal pathology.
Adrian Gh. Podoleanu, George M. Dobre, Radu G. Cucu, Richard B. Rosen, Patricia Garcia, Juan Nieto, Daniel V. Will, Ronald C. Gentile, Thomas Muldoon, Joseph B. Walsh, Lawrence A. Yannuzzi, Yale Fisher, Dennis A. Orlock, Rishard Weitz, John Rogers, Shane Dunne, Aaron B. Boxer, "Combined multiplanar optical coherence tomography and confocal scanning ophthalmoscopy," Journal of Biomedical Optics 9(1), (1 January 2004). http://dx.doi.org/10.1117/1.1627778
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KEYWORDS
Optical coherence tomography

Confocal microscopy

Eye

Retina

Image resolution

Scanners

Tissues

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