1 July 2004 Low-intensity indocyanine-green laser phototherapy of acne vulgaris: Pilot study
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J. of Biomedical Optics, 9(4), (2004). doi:10.1117/1.1756596
Abstract
Near infrared (NIR) diode laser low-intensity (soft) phototherapy with the topical application of indocyanine green (ICG) has been suggested for treatment of acne vulgaris. Twelve volunteers with acne lesions on their faces and/or backs were enrolled in the experiment. Skin areas of the subjects that were 4×5 cm2 were stained with ICG solution for 5 min before laser irradiation (803 nm) at a power density up to 50 mW/cm2 for 5 to 10 min. For 75% of the subjects, a single treatment was provided and for the other 25%, eight sequential treatments over a period of a month were carried out. Observations a month after the completion of the treatment showed that only the multiple treatments with a combination of ICG and NIR irradiation reduced inflammation and improved the state of the skin for a month without any side effects. A month after treatment, the improvement was about 80% for the group receiving multiple treatments. Single treatments did not have a prolonged effect.
Elina A. Genina, Alexey N. Bashkatov, Georgy V. Simonenko, Olga D. Odoevskaya, Valery V. Tuchin, Gregory B. Altshuler, "Low-intensity indocyanine-green laser phototherapy of acne vulgaris: Pilot study," Journal of Biomedical Optics 9(4), (1 July 2004). http://dx.doi.org/10.1117/1.1756596
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KEYWORDS
Skin

Near infrared

Laser irradiation

Phototherapy

Luminescence

Semiconductor lasers

Inflammation

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