1 July 2004 Spectroscopic detection of bladder cancer using near-infrared imaging techniques
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Abstract
High-contrast imaging of bladder cancer is demonstrated using near-infrared autofluorescence under long-wavelength laser excitation in combination with cross-polarized elastic light scattering. Fresh unprocessed surgical specimens obtained following cystectomy or transurethral resection were utilized and a set of images for each tissue sample was recorded. These images were compared with the histopathology of the tissue sample. The experimental results indicate that the intensity of the near-infrared emission as well as that of the cross-polarized backscattered light was considerably different in cancer tissues than in that of the contiguous nonneoplastic tissues, allowing an accurate delineation of a tumor's margins.
© (2004) Society of Photo-Optical Instrumentation Engineers (SPIE)
Stavros G. Demos, Stavros G. Demos, Regina Gandour-Edwards, Regina Gandour-Edwards, Rajen Ramsamooj, Rajen Ramsamooj, Ralph de Vere White, Ralph de Vere White, } "Spectroscopic detection of bladder cancer using near-infrared imaging techniques," Journal of Biomedical Optics 9(4), (1 July 2004). https://doi.org/10.1117/1.1753587 . Submission:
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