1 April 2005 Comparison of a CMOS-based and a CCD-based digital x-ray imaging system: Observer studies
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The purpose of this study is to compare the performance of a complementary metal–oxide–semiconductor (CMOS)-based digital x-ray imaging system with that of a charge-coupled device (CCD)-based system for small animal research. A CMOS-based digital x-ray imaging system was developed and tested. The core of this system is a detector module consisting of eight joint CMOS chips, each having a size of 512×1024 pixels with a readout unit on the side. The pixel size of the CMOS detectors is 0.048 mm. The contrast detail detectability of the CMOS-based system was studied using different phantoms, and compared with that of a CCD-based digital imaging system. The contrast detail curves of the CMOS-based image system, obtained from the observer-based studies, are highly comparable to the CCD-based imaging system, particularly at higher x-ray exposures. The images of fine structures of a mouse, acquired by the CMOS system, demonstrated the capability of the system in the studies of small animals. With integration potential, manufacturability, and low costs, the CMOS-based imaging systems could be used in animal studies and potentially become useful clinical tools for diagnosis.
© (2005) Society of Photo-Optical Instrumentation Engineers (SPIE)
Qirong Zhang, Qirong Zhang, Yuhua Li, Yuhua Li, Ben Steele, Ben Steele, Xizeng Wu, Xizeng Wu, Wei R. Chen, Wei R. Chen, John X. Rong, John X. Rong, Hong Liu, Hong Liu, } "Comparison of a CMOS-based and a CCD-based digital x-ray imaging system: Observer studies," Journal of Electronic Imaging 14(2), 023002 (1 April 2005). https://doi.org/10.1117/1.1902763 . Submission:

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