Demonstration of synchrotron x-ray phase contrast imaging computed tomography of infiltrative transitional cell carcinoma of the prostatic urethra in a dog

James E. Montgomery; Michael  J. Wesolowski; Bailey Wolkowski; Rajni Chibbar; Elisabeth C.  R. Snead; Jaswant Singh; Murray Pettitt; Pritpal S. Malhi; Trinita Barboza; Gregg Adams

doi:10.1117/1.JMI.3.1.015504

14 March 2016 Demonstration of synchrotron x-ray phase contrast imaging computed tomography of infiltrative transitional cell carcinoma of the prostatic urethra in a dog

James E. Montgomery, Michael J. Wesolowski, Bailey Wolkowski, Rajni Chibbar, Elisabeth C. R. Snead, Jaswant Singh, Murray Pettitt, Pritpal S. Malhi, Trinita Barboza, Gregg Adams

Author Affiliations +

Journal of Medical Imaging, Vol. 3, Issue 1, 015504 (March 2016). https://doi.org/10.1117/1.JMI.3.1.015504

Abstract

Prostatic urethral transitional cell carcinoma with prostatic invasion in a dog was imaged with abdominal radiography and abdominal ultrasonography antemortem. Synchrotron in-line x-ray phase contrast imaging computed tomography (XPCI-CT) was performed on the prostate ex vivo at the Canadian Light Source Synchrotron and compared to histology. XPCI-CT imaging provides greater soft tissue contrast than conventional absorption-based x-ray imaging modalities, permitting visualization of regions of inflammatory cell infiltration, differentiation of invasive versus noninvasive tumor regions, and areas of necrosis and mineralization. This represents the first report of XPCI-CT images of an invasive prostatic urothelial neoplasm in a dog.

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James E. Montgomery, Michael J. Wesolowski, Bailey Wolkowski, Rajni Chibbar, Elisabeth C. R. Snead, Jaswant Singh, Murray Pettitt, Pritpal S. Malhi, Trinita Barboza, and Gregg Adams "Demonstration of synchrotron x-ray phase contrast imaging computed tomography of infiltrative transitional cell carcinoma of the prostatic urethra in a dog," Journal of Medical Imaging 3(1), 015504 (14 March 2016). https://doi.org/10.1117/1.JMI.3.1.015504

Published: 14 March 2016

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