Open Access
31 March 2017 History and future technical innovation in positron emission tomography
Terry Jones, David W. Townsend
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Abstract
Instrumentation for positron emission tomography (PET) imaging has experienced tremendous improvements in performance over the past 60 years since it was first conceived as a medical imaging modality. Spatial resolution has improved by a factor of 10 and sensitivity by a factor of 40 from the early designs in the 1970s to the high-performance scanners of today. Multimodality configurations have emerged that combine PET with computed tomography (CT) and, more recently, with MR. Whole-body scans for clinical purposes can now be acquired in under 10 min on a state-of-the-art PET/CT. This paper will review the history of these technical developments over 40 years and summarize the important clinical research and healthcare applications that have been made possible by these technical advances. Some perspectives for the future of this technology will also be presented that promise to bring about new applications of this imaging modality in clinical research and healthcare.
© 2017 Society of Photo-Optical Instrumentation Engineers (SPIE) 2329-4302/2017/$25.00 © 2017 SPIE
Terry Jones and David W. Townsend "History and future technical innovation in positron emission tomography," Journal of Medical Imaging 4(1), 011013 (31 March 2017). https://doi.org/10.1117/1.JMI.4.1.011013
Received: 12 February 2017; Accepted: 14 March 2017; Published: 31 March 2017
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CITATIONS
Cited by 174 scholarly publications and 1 patent.
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KEYWORDS
Positron emission tomography

Scanners

Sensors

Brain

Neuroimaging

Medicine

Scintillators

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