6 November 2017 H-scan sensitivity to scattering size
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In the H-scan analysis and display, visualization of different scattering sizes and types is enabled by a matched filter approach involving different orders of Gaussian weighted Hermite functions. An important question with respect to clinical applications involves the change in H-scan outputs with respect to small changes in scatterer sizes. The sensitivity of H-scan outputs is analyzed using the theory of backscatter from a compressible sphere. Experimental corroboration is established using mono dispersed spherical scatterers in phantoms. With a 6-MHz center frequency broadband transducer, it is possible to visualize changes in scattering size in the order of 10 to 15    μ m in phantoms and also changes in ex vivo bovine liver tissue due to edema caused by hypotonic perfusion.
© 2017 Society of Photo-Optical Instrumentation Engineers (SPIE)
Mawia Khairalseed, Mawia Khairalseed, Kenneth Hoyt, Kenneth Hoyt, Juvenal Ormachea, Juvenal Ormachea, Alberto Terrazas, Alberto Terrazas, Kevin J. Parker, Kevin J. Parker, } "H-scan sensitivity to scattering size," Journal of Medical Imaging 4(4), 043501 (6 November 2017). https://doi.org/10.1117/1.JMI.4.4.043501 . Submission: Received: 13 July 2017; Accepted: 12 October 2017
Received: 13 July 2017; Accepted: 12 October 2017; Published: 6 November 2017

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